OXYTETRACYCLINE HYDROCHLORIDE
SYNONYM: HYDROXYTETRACYCLINE MONOHYDROCHLORIDE;
5-HYDROXYTETRACYCLINE HYDROCHLORIDE; MEDEMYCIN;
FORMULA: C22H25ClN2O9
M. W.: 496.90
CAS NO.: 2058-46-0
GRADE: BP2000/USP24
DESCRIPTION: A YELLOW CRYSTALLINE
POWDER. IDENTIFICATION IS POSITIVE.
SPECIFICATIONS:
|
ITEM
|
BP2000
|
USP24
|
|
IDENTIFICATION
|
A. B. C. POSITIVE
|
A. ABSORPTIVITY
88.2-96.8% (335nm)
B. POSITIVE
|
|
PH VALUE
|
2.4-2.9
|
2.0-3.0
|
|
LOSS ON DRYING
|
---
|
2.0% MAX.
|
|
SPECIAL OPTICAL ROTATION
|
-188o—200o
|
---
|
|
ABSORBANCE
|
270-290
|
---
|
|
LIGHT0ABSORBING
IMPURITIES
|
430nm≤0.50
490nm≤0.20
|
---
|
|
RELATED SUBSTANCE
|
4-EPIOXYTETRACYCLINE≤0.5%
|
---
|
|
TETRACYCLINE≤2.0%
|
|
THE TOTAL AREA OF THE PEAKS
OF
(αTOβ)-APO-OXYTETRACYCLINE≤2.0%
|
|
THE AREA OF ANY PEAK
APPEARING ON THE TAIL OF THE MAIN PEAK≤2.0%
|
|
HEAVY METALS
|
50PPM MAX.
|
---
|
|
WATER
|
2.0% MAX.
|
---
|
|
SULPHATE ASH
|
0.5% MAX.
|
---
|
|
POTENCY (HPLC) (μg/mg)
|
---
|
835 MIN.
(ANHYDROUS)
|
|
ASSAY (HPLC)
|
95.0-100.5% (ANHYDROUS)
|
---
|
PACKING: PACKED IN 25KGS CARDBOARD
DRUM. 9MT/FCL.
